Domenico Gatti’s Laboratory: structural and computational biology

Our research focuses on four key areas:

1. X-ray crystallography of chaperones of F1F0 ATPase and enzymes involved in polysaccharide biosynthesis

2. QM/MM and Metadynamics simulations of enzymatic reactions

3. Simulation and analysis of coevolution in proteins

4. Finite Element Methods (FEM) of axonal microtubules

  • Coevolution maps recorded by our Matlab program MSAVOLVE during the in silico evolution of a protein from a hypothetical ancestor.                             

Domenico L. Gatti MD PhD, School of Medicine of Wayne State University, Scott Hall, 540 E. Canfield Avenue, Detroit, MI 48201 - US © Domenico Gatti 2016